Preliminary Program

Wednesday - July 3rd, 2019

Time Sala Baldaquino Sala Fogón
08:00 Technical Secretariat opens for Registration
09:00 - 11:00 Session 1:
New in vivo tools in Pharmacology: CRISPR/Cas and conditional mice

Moderators: Mª Ángeles Moro and Lluis Montoliu
- Lluís Montoliu. CNB. Madrid, Spain
- Sagrario Ortega. CNIO. Madrid, Spain
- "Investigation of Rodent Adult Neurogenesis in Homeostasis and Disease: an example of the use of Conditional Mice in Neuropharmacology". Mª Ángeles Moro. Universidad Computense. Madrid, Spain
11:00 - 12:00 Coffee Break and Poster Session 1
12:00 - 12:30 Opening Ceremony
12:30 - 13:30 Opening Lecture
"Stop the Mast Cells and the Eosinophils by any means!" Francesca Levi-Schaffer. IUPHAR, Jerusalem, Israel
13:30 - 15:00 Lunch and Poster Session 1
15:00 - 16:00 Plenary Lecture
Nathalie Vergnolle. Toulouse, France
16:00 - 16:30 Coffee Break and Poster Session 1
16:30 - 18:30 Session 2:
New targets in cardiac and cardiovascular disorders

Moderators: Ricardo Caballero and Thomas Wieland
- Thomas Wieland, Mannheim, Germany
- Ricardo Caballero. Madrid, Spain
- "Interventions in WNT Signaling Ctimulate Cardiac Regeneration". Mattijs Blankesteijn. Maastricht, Netherland

Oral communications
Abstracts Title:
- "Systemic Inflammation is Reduced in Primary Hypercholesterolemia Patients after an Oral Fat Load Administration"
- "Probiotics Prevent Hypertension in a Murine Model of Systemic Lupus Erythematosus Induced by TLR7 Activation"
Session 3:
Parallel Roundtable. Education in Pharmacology.

Moderators: Michael Spedding and Concha Peiró
- Michael Spedding, IUPHAR, Edimburgh, UK
- "The Doctoral Programme in Pharmacology, University of Chile". Guillermo Díaz. Santiago Chile
- Jose Miguel Doña Rodríguez. ULPGC. Las Palmas, Spain

Oral communications
Abstracts Title:
- "Combination of Innovative Teaching Techniques in Pharmacology Seminar Classes"
- "Information about Drugs and Related Topics in the Spanish General, Economic and Professional Press"
20:00 Welcome Reception

Thursday - July 4th, 2019

Time Sala Baldaquino Sala Fogón
08:00 Technical Secretariat opening time
09:00 - 11:00 Session 4:
Open innovation in drug discovery

Moderator: María Jesús Sanz.
- Isabel Colomina. President of AEMICE
- María del Buensuceso Fernández
- Ayoze González
Sponsored by NOVARTIS
Session 5:
Young Scientist Forum
Part 1

Moderators: Cristina Arce, Marta Cimadevila and Aida Collado
- "Creativity in Science". Michael Spedding. IUPHAR, Edimburg, UK
Part 2
Moderators: Jesús Cosín, Patrice Marques, Alejandra Romero and Álvaro San Hipólito
- "How to become a good University Professor". María Luisa Ferrándiz. University of Valencia, Valencia, Spain
- "Research after PhD". Nuria Godessart.
- "From Science to Industry". Amadeu Gavaldá. Almirall, Barcelona, Spain
- "How to bring Science to Society: from School to Parliament". Eduardo Oliver. CNIC, Madrid, Spain
Sponsored by Almirall
11:00 - 11:30 Coffee Break and Poster Session 2
11:30 - 13:30 Session 6:
New advances in the Pharmacology of Respiratory System
Moderators: Angel Cogolludo and Andreas Ludwig
- Angel Cogolludo. Madrid, Spain
- Andreas Ludwig. Aachen, Germany

Oral communications
Abstracts Title:
- "Role of il-11 in Pulmonary Fibrosis Associated to Pulmonary Hypertension"
- "The Role of MUC1 in a Bleomycin Induced Pulmonary Fibrosis Mouse Model"
Session 7:
New advances in Neuropharmacology

Moderators: Ricardo Borges and Ramón Sotomayor
- "Inside a Secretory Vesicle. Novel Targets for Modulating the Exocytosis of Neurotransmitters". Ricardo Borges Jurado. Tenerife, Spain
- José Guzmán González. Santiago, Chile
- Ramon Sotomayor Zárate. Santiago, Chile
- Izaskun Buendia Abaitua. UAM. Madrid, Spain
13:30 - 15:00 Lunch and Poster Session 2
15:00 - 16:00 Plenary Lecture
"Somatic Mutations and Clonal Hematopoiesis as Drivers of Inflammation and Cardiovascular Disease". José Javier Fuster. CNIC. Madrid, Spain
16:00 - 16:30 Coffee Break and Poster Session 2
16:30 - 18:30 Session 8:
Free Radicals in traslational Pharmacology.

Moderators: María José Alcaraz and Pietro Ghezzi
- María José Alcaraz. Valencia, Spain
- Ana Casas. Maastricht, Netherland
- Pietro Ghezzi. Sussex, UKbr>

Oral communications
Abstracts Title:
- "Role of il-11 in Pulmonary Fibrosis Associated to Pulmonary Hypertension"
- "The Role of MUC1 in a Bleomycin Induced Pulmonary Fibrosis Mouse Model"
Session 9:
Poster Presentation (8 selected posters)

Moderators: Mabel Loza and Juan Manuel Duarte
Abstracts Titles:
- "CCL11/CCR3 Axis is Involved Atherosclerosis Development"
- "The Adipokine Visfatin Induces Endothelial Dysfunction through TLR-4 and NLRP3 Inflammasome Activation."
- "Characterization and Evaluation of Hemp Protein Hydrolysates on Neuroprotection"
- "Obesity-Induced Hypogonadism: Pathophysiological Roles of a Novel Hypothalamic miRNA/Kisspeptin Pathway and Potential Therapeutic Implications"
- "In vitro Characterization of a TRPV1 Soft Antagonist"
- "Quantification of Functional Bias of Serotonin 5-HT2A Receptor Agonists and Validation of Structural Hypotheses on Functional Selectivity at 5-HT2A Receptor"
- "MUC1-CT as an IPF Potential Druggable Target"

Friday - July 5th, 2019

Time Sala Baldaquino Sala Fogón
08:00 Technical Secretariat opening time
09:00 - 11:00 Session 10:
Aging from mechanisms to pharmacological perspectives

Moderators: José Viña and Jorge Fuentealba
- José Viña. Valencia, Spain
- "P2XR Overexpression Contribute to Beta Amyloid Toxicity: New Pharmacological Target to AD". Jorge Fuentealba Arcos. Concepción, Chile
- "Cardiac Fibroblast Role on Inflammatory Process: Interaction with Immune Cells". Guillermo Díaz. Santiago, Chile

Oral communications
Abstracts Title:
- "Targeting Soluble Epoxide Hydrolase to Improve Neurodegenerative Traits in SAMP8 Mouse"
- "The Angiotensin-(1-7)/Mas Receptor Axis Attenuates Human Endothelial Cells Senescence through the Activation of Klotho and Nrf2"
Session 11:
New Advances in the Pharmacology of Cancer

Moderators: Francisco Estévez Sarmiento and Patricia Rijo
- "Abietane diterpenoids from Plectranthus spp. as Lead Protein Kinase C Modulators for Cancer Therapy". Patricia Rijo. Lisboa, Portugal
- Francisco Estévez Sarmiento. Las Palmas, Spain
- Anna Meseguer Navarro. Barcelona, Spain

Oral communications
Abstracts Title:
- "CM-728 as a Potential and Novel Compound for Metastatic Clear Cell Renal Cell Carcinoma (ccRCC) Treatment"
- "Preliminary Screening for Selective Anticancer Activity of Andalusian Plants"
11:00 - 11:30 Coffee Break
11:30 - 12:30 Session 12
Oral Communications (I): Pain and Inflammation

Moderators: Francesca Levi-Schaffer and Eva Delpón
Abstracts Title:
- "Amitriptyline, a New Therapeutic Tool to Block Innate Immune Responses in Osteoarthritis Patients"
- "Antiinflammatory Effect of Osteostatin in Monosodium Urate Crystal-Induced Gouty Arthritis Model"
- "Methadone is an analgesic with Low Addictive Side Effects due to its Weak Potency on Opioid-Galanin Receptor Heteromers"
- "Identification and Validation of two small Molecules Targeting the IL-17 Inflammatory Pathway"
Session 13
Oral Communications: Neuro/Psychopharmacology and Cardiac Pharmacology

Moderators: Paco Ciruela and Mattijs Blankesteijn
Abstracts Title:
- "Protective Effect of Phosphorus Dendrimers in a Murine Model of Multiple Sclerosis"
- "NLRP3 Inflammasome Inhibition Protects the Neurovascular Unit, Reduces Infarct Volume and Inflammation in Cerebral Ischemia"
12:30 - 13:30 Closing Lecture
Mauro Perretti. London, UK
Sponsored by EPHAR
13:30 - 14:00 Closing Ceremony
14:00 - 15:30 Lunch
15:30 - 17:30 SEF Assembly
21:00 Gala Dinner

The SEF’2019 Congress, will focus in the following thematic areas:

  • Cardiovascular
  • Clinic Pharmacology
  • Cancer
  • Drug Safety and Toxicology
  • Endocrinology
  • Gastrointestinal/Respiratory Pharmacology
  • Neuro/Psycho Pharmacology
  • Pharmacogenetics
  • Pharmacology of Pain and lnflammation
  • Receptors
  • Drug Design
  • Teaching